Functionalization of Multi-Walled Carbon Nanotubes by 1-Amino-2-Naphthol-4-Sulfonic Acid and Study of Their Antimicrobial Activity Against The Gram-negative and Gram-positive Bacterias

In this study, we investigated the chemical functionalization of carboxylated multiwalled carbon nanotubes (MWCNT–COOH) by 1-Amino-2-naphthol-4-sulfonic acid (ANSA). The functionalized MWCNTs exhibited good aqueous solubility due to the presence of the –OH and – SO3H groups of ANSA. The antimicrobial activity of the MWCNT–COOH as well as its functionalized multiwall nanotube MWCNT-CO-2-(1-amino-2-naphthol-4-sulfonic acid) was tested against some gram-negative and gram-positive bacterias. In vitro studies, MWCNTSANSA represented a significant enhancement in the antimicrobial capability of MWCNTs against gram-negative E. coli and S. typhimurium bacterias. Therefore, these functionalized carboxylated multiwall nanotubes could potentially be considered as antimicrobial candidates.